Values of fine-needle aspiration cytology of parotid gland tumors: A review of 996 cases at a single institution

Head Neck. 2019 Feb;41(2):358-365. doi: 10.1002/hed.25503. Epub 2018 Dec 9.

Abstract

Background: We evaluated the diagnostic accuracy of fine-needle aspiration cytology (FNAC) in a large series of benign and malignant parotid tumors.

Methods: The FNAC diagnosis of 821 benign and 175 malignant parotid tumors managed at our department between 1999 and 2017 was correlated with the final histology.

Results: FNAC made a correct histopathological diagnosis in 72% of the benign parotid tumors; however, FNAC provided a correct grade in only 34% of the malignant tumors. FNAC correctly identified the histology of 94% of pleomorphic adenomas subsequently confirmed by histopathological examination. The sensitivity, specificity, and diagnostic accuracy of FNAC for detecting malignancy were 82.3%, 98.7%, and 95.9%, respectively.

Conclusion: FNAC generally provided the correct histological diagnosis for benign tumors. However, the histological evaluation and grading of malignant tumors were poor. Although FNAC showed good sensitivity, specificity, and accuracy, its sensitivity decreased when nondiagnostic cases were included in the analysis.

Keywords: Warthin's tumor; accuracy; fine-needle aspiration cytology; parotid gland tumors; pleomorphic adenoma.

MeSH terms

  • Adenolymphoma / mortality
  • Adenolymphoma / pathology*
  • Adenolymphoma / therapy
  • Adenoma / mortality
  • Adenoma / pathology*
  • Adenoma / therapy
  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Biopsy, Fine-Needle*
  • Carcinoma / mortality
  • Carcinoma / pathology*
  • Carcinoma / therapy
  • Female
  • Humans
  • Male
  • Middle Aged
  • Parotid Neoplasms / mortality
  • Parotid Neoplasms / pathology*
  • Parotid Neoplasms / therapy
  • Retrospective Studies
  • Sensitivity and Specificity
  • Young Adult