Efficacy of Ruxolitinib Therapy in a Patient With Severe Enterocolitis Associated With a STAT3 Gain-of-Function Mutation

Affiliations

• ¹ Inserm UMR1163, Intestinal Immunity, Institut Imagine, Paris, France.
• ² Inserm UMR1163, Intestinal Immunity, Institut Imagine, Paris, France; Université Paris Descartes Sorbonne Paris Cité, Paris, France; Assistance Publique des Hôpitaux de Paris (AP-HP), Pediatric Gastroenterology, Hôpital Necker-Enfants Malades, Paris, France.
• ³ Inserm UMR1163, Intestinal Immunity, Institut Imagine, Paris, France; Assistance Publique des Hôpitaux de Paris (AP-HP), Pediatric Gastroenterology, Hôpital Necker-Enfants Malades, Paris, France.
• ⁴ Inserm UMR1163, Intestinal Immunity, Institut Imagine, Paris, France; Université Paris Descartes Sorbonne Paris Cité, Paris, France.
• ⁵ Université Paris Descartes Sorbonne Paris Cité, Paris, France; Assistance Publique des Hôpitaux de Paris (AP-HP), Pediatric Gastroenterology, Hôpital Necker-Enfants Malades, Paris, France; AP-HP, Pathology, Hôpital Necker-Enfants Malades, Paris, France.
• ⁶ AP-HP, Gastroenterology Hôpital Européen Georges Pompidou, Paris, France.
• ⁷ Biological Hematology, Hôpital Necker Enfants Malades, Paris, France.
• ⁸ Université Paris Descartes Sorbonne Paris Cité, Paris, France; AP-HP, Study Center of Primary Immunodeficiency, Hôpital Necker-Enfants Malades, Paris, France.
• ⁹ Université Paris Descartes Sorbonne Paris Cité, Paris, France; Inserm UMR1163, Immunogenetics of Pediatric Autoimmune Diseases, Institut Imagine, Paris, France.
• ¹⁰ Inserm UMR 1160, Paris, France.
• ¹¹ Inserm UMR 1160, Paris, France; AP-HP Gastroenterology Hôpital Saint Louis, Université Paris, Diderot, France.
• ¹² Inserm UMR1163, Intestinal Immunity, Institut Imagine, Paris, France; Assistance Publique des Hôpitaux de Paris (AP-HP), Pediatric Gastroenterology, Hôpital Necker-Enfants Malades, Paris, France; AP-HP, Pathology, Hôpital Necker-Enfants Malades, Paris, France.
• ¹³ Inserm UMR1163, Intestinal Immunity, Institut Imagine, Paris, France; Université Paris Descartes Sorbonne Paris Cité, Paris, France; AP-HP, Gastroenterology Hôpital Européen Georges Pompidou, Paris, France.
• ¹⁴ Université Paris Descartes Sorbonne Paris Cité, Paris, France; Hematology, Hôpital Necker Enfants Malades, Paris, France.
• ¹⁵ Inserm UMR1163, Intestinal Immunity, Institut Imagine, Paris, France; Université Paris Descartes Sorbonne Paris Cité, Paris, France. Electronic address: [email protected].
• ¹⁶ Inserm UMR1163, Intestinal Immunity, Institut Imagine, Paris, France; Université Paris Descartes Sorbonne Paris Cité, Paris, France; AP-HP, Gastroenterology, Hôpital Cochin, Paris, France. Electronic address: [email protected].