Abstract
Cancer cells consume and utilize glucose at a higher rate than normal cells. However, some microenvironments limit the availability of nutrients and glucose. In 2018, researchers found that tumours depend on a variety of different nutrient sources, both locally and systemically, to overcome metabolic limitations and promote tumour progression and metastasis.
Publication types
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Comparative Study
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Research Support, N.I.H., Extramural
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Research Support, U.S. Gov't, Non-P.H.S.
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Review
MeSH terms
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Asparagine / metabolism*
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Aspartic Acid / metabolism*
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Disease Progression
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Female
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Humans
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Lactic Acid / metabolism
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Male
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Neoplasms / pathology
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Neoplasms / physiopathology
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Oxygen Consumption / physiology
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Proteins / metabolism
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Reference Values
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Tumor Cells, Cultured / metabolism*
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Tumor Microenvironment*
Substances
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Proteins
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Aspartic Acid
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Lactic Acid
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Asparagine