Severe Disseminated Infection with Emerging Lineage of Methicillin-Sensitive Staphylococcus aureus

Emerg Infect Dis. 2019 Jan;25(1):187-189. doi: 10.3201/eid2501.180684.

Abstract

We report a case of severe disseminated infection in an immunocompetent man caused by an emerging lineage of methicillin-sensitive Staphylococcus aureus clonal complex 398. Genes encoding classic virulence factors were absent. The patient made a slow recovery after multiple surgical interventions and a protracted course of intravenous flucloxacillin.

Keywords: Antimicrobial resistance; MRSA; MRSA and other staphylococci; MSSA; Staphylococcus aureus; bacteria; epidural abscess; flucloxacillin; methicillin-resistant Staphylococcus aureus; methicillin-sensitive Staphylococcus aureus; psoas abscess; retropharyngeal abscess; virulence factors.

Publication types

  • Case Reports

MeSH terms

  • Administration, Intravenous
  • Anti-Bacterial Agents / administration & dosage*
  • Floxacillin / administration & dosage*
  • Humans
  • Immunocompetence
  • Magnetic Resonance Imaging
  • Male
  • Methicillin / pharmacology
  • Middle Aged
  • Staphylococcal Infections / diagnostic imaging*
  • Staphylococcal Infections / drug therapy
  • Staphylococcal Infections / microbiology
  • Staphylococcal Infections / surgery
  • Staphylococcus aureus / drug effects
  • Staphylococcus aureus / isolation & purification*
  • Tomography, X-Ray Computed
  • Treatment Outcome
  • Whole Genome Sequencing

Substances

  • Anti-Bacterial Agents
  • Floxacillin
  • Methicillin