A Rare Case of Neutrophil-Rich, ALK-Negative Anaplastic Large Cell Lymphoma in the Lung Mimicking a Pulmonary Abscess on 18F-FDG PET/CT

Clin Nucl Med. 2019 Mar;44(3):234-237. doi: 10.1097/RLU.0000000000002419.

Abstract

A 21-year-old man complained of cough, fever, and hemoptysis for 15 days. Peripheral neutrophil cell (33.8 × 10/L) was markedly increased, and a mass in the left lung was detected by chest radiography. F-FDG PET/CT was referred for characterizing the lesion and found a large mass with multiple cavities in the left lung, which had markedly high uptake of F-FDG, mimicking pulmonary abscess. Surprisingly, the lesion was eventually proved to be neutrophil-rich anaplastic large cell lymphoma. After 4 cycles' chemotherapy, the lesion shrank significantly.

Publication types

  • Case Reports

MeSH terms

  • Diagnosis, Differential
  • Fluorodeoxyglucose F18
  • Humans
  • Lung Abscess / diagnostic imaging*
  • Lung Neoplasms / diagnostic imaging*
  • Lymphoma, Large-Cell, Anaplastic / diagnostic imaging*
  • Male
  • Positron Emission Tomography Computed Tomography*
  • Radiopharmaceuticals
  • Young Adult

Substances

  • Radiopharmaceuticals
  • Fluorodeoxyglucose F18