Fate Mapping of Sca1+ Cardiac Progenitor Cells in the Adult Mouse Heart

Juan Tang; Yan Li; Xiuzhen Huang; Lingjuan He; Libo Zhang; Haixiao Wang; Wei Yu; Wenjuan Pu; Xueying Tian; Yu Nie; Shengshou Hu; Qing-Dong Wang; Kathy O Lui; Bin Zhou

doi:10.1161/CIRCULATIONAHA.118.036210

Fate Mapping of Sca1⁺ Cardiac Progenitor Cells in the Adult Mouse Heart

Circulation. 2018 Dec 18;138(25):2967-2969. doi: 10.1161/CIRCULATIONAHA.118.036210.

Authors

Juan Tang^{1

2}, Yan Li^{1

2}, Xiuzhen Huang^{1

2}, Lingjuan He^{1

2}, Libo Zhang^{1

2}, Haixiao Wang¹, Wei Yu^{1

2}, Wenjuan Pu^{1

2}, Xueying Tian³, Yu Nie⁴, Shengshou Hu⁴, Qing-Dong Wang⁵, Kathy O Lui⁶, Bin Zhou^{1

2

3

7}

Affiliations

¹ State Key Laboratory of Cell Biology, CAS Center for Excellence in Molecular Cell Science, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, University of Chinese Academy of Sciences (J.T., Y.L., X.H., L.H., L.Z., H.W., W.Y., W.P., B.Z.).
² Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences (J.T., Y.L., X.H., L.H., L.Z., W.Y., W.P., B.Z.).
³ Key Laboratory of Regenerative Medicine of Ministry of Education, Institute of Aging and Regenerative Medicine, Jinan University, Guangzhou, China (X.T., B.Z.).
⁴ State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Disease, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing (Y.N., S.H.).
⁵ Bioscience Heart Failure, Cardiovascular, Renal and Metabolism, IMED Biotech Unit, AstraZeneca, Gothenburg, Sweden (Q.-D.W.).
⁶ Department of Chemical Pathology; Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong (K.O.L.).
⁷ School of Life Science and Technology, ShanghaiTech University, China (B.Z.).

PMID: 30566021
DOI: 10.1161/CIRCULATIONAHA.118.036210

No abstract available

Keywords: Sca1+; cardiac progenitor cell; cardiac regeneration; cardiomyocyte; myocardial infarction.

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Adult Stem Cells / physiology*
Animals
Antigens, Ly / genetics
Antigens, Ly / metabolism*
Cell Differentiation
Cell Lineage
Cell Self Renewal
Cells, Cultured
Disease Models, Animal
Endothelial Cells / physiology*
Fibroblasts / physiology*
Flow Cytometry
Homeostasis
Humans
Membrane Proteins / genetics
Membrane Proteins / metabolism*
Mice
Mice, Transgenic
Muscle Development
Myocardial Infarction / physiopathology*
Myocytes, Cardiac / physiology*
Receptor, Platelet-Derived Growth Factor alpha / metabolism
Tamoxifen

Substances

Antigens, Ly
Ly6a protein, mouse
Membrane Proteins
Tamoxifen
Receptor, Platelet-Derived Growth Factor alpha