Vanishing spleen syndrome post right partial nephrectomy in a sicklemic patient

Pan Afr Med J. 2018 Jul 16:30:211. doi: 10.11604/pamj.2018.30.211.15454. eCollection 2018.

Abstract

Splenic infarction after contralateral laparoscopic renal surgery has not, to our knowledge, been reported. The spleen is the most affected organ in sickle cell disease and the mechanism of auto infarction is thought to result from the crystallization of abnormal hemoglobin during periods of hypoxia or acidosis resulting in parenchymal ischemia and ultimately tissue necrosis. We report a case of 45 year old female with sickle cell disease who had an unremarkable spleen at the time of a laparoscopic right partial nephrectomy and was subsequently found to have marked diminution in her splenic volume.

Keywords: Splenic infarction; laparoscopic renal surgery; right partial nephrectomy; sickle cell disease.

Publication types

  • Case Reports

MeSH terms

  • Anemia, Sickle Cell / complications*
  • Female
  • Hemoglobins / metabolism
  • Humans
  • Laparoscopy / adverse effects
  • Laparoscopy / methods*
  • Middle Aged
  • Nephrectomy / adverse effects
  • Nephrectomy / methods*
  • Parenchymal Tissue / blood supply
  • Parenchymal Tissue / pathology
  • Splenic Infarction / diagnosis*
  • Splenic Infarction / etiology
  • Syndrome

Substances

  • Hemoglobins