Gender difference in clinical conditions among hospitalized adults with myotonic dystrophy

Muscle Nerve. 2019 Mar;59(3):348-353. doi: 10.1002/mus.26402. Epub 2019 Jan 13.

Abstract

Introduction: In this study we examined gender differences in adult hospitalizations with myotonic dystrophy (DM).

Methods: From the Nationwide Inpatient Sample (NIS) 2010-2014, we identified 1,891 adult hospitalizations with a DM diagnosis and constructed a comparison group of hospitalizations without DM using propensity score matching. We calculated relative risk by gender for 44 clinical diagnoses that each accounted for at least 5% of DM hospitalizations.

Results: Hospitalizations with DM were longer (4.8 vs. 4.1 days, P < 0.0001) and more costly ($13,241 vs. $11,458, P < 0.0001) than those without DM. More than half (25 of 44) of the conditions co-occurring with DM hospitalizations did not differ in their relative risks by gender. For those that differed by gender, only 5 were specific to DM, compared with hospitalizations without DM.

Discussion: Our findings highlight the importance of comprehensive and coordinated care for DM rather than gender-oriented care in the inpatient setting. Muscle Nerve 59:348-353, 2019.

Keywords: DM; co-occurring conditions; gender differences; hospitalizations; matching.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Female
  • Hospital Costs
  • Hospitalization
  • Humans
  • International Classification of Diseases
  • Male
  • Middle Aged
  • Myotonic Dystrophy / economics
  • Myotonic Dystrophy / physiopathology*
  • Propensity Score
  • Retrospective Studies
  • Risk
  • Risk Assessment
  • Sex Characteristics
  • Socioeconomic Factors
  • Young Adult