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©Hsiao-Hsien Rau, Yi-Syuan Wu, Chi-Ming Chu, Fu-Chung Wang, Min-Huei Hsu, Chi-Wen Chang, Kang-Hua Chen, Yen-Liang Lee, Senyeong Kao, Yu-Lung Chiu, Hsyien-Chia Wen, Anis Fuad, Chien-Yeh Hsu, Hung-Wen Chiu. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 09.06.2017.