Greater Odds for Angina in Uranium Miners Than Nonuranium Miners in New Mexico

J Occup Environ Med. 2019 Jan;61(1):1-7. doi: 10.1097/JOM.0000000000001482.

Abstract

Objective: The aim of this study was to test the hypothesis that uranium miners in New Mexico (NM) have a greater prevalence of cardiovascular disease than miners who extracted the nonuranium ore.

Methods: NM-based current and former uranium miners were compared with nonuranium miners by using cross-sectional standardized questionnaire data from the Mining Dust in the United States (MiDUS) study from 1989 to 2016.

Results: Of the 7215 eligible miners, most were men (96.3%). Uranium miners (n = 3151, 43.7%) were older and diabetic, but less likely to currently smoke or use snuff (P ≤ 0.001 for all). After adjustment for covariates, uranium miners were more likely to report angina (odds ratio 1.51, 95% confidence interval 1.23 to 1.85) than nonuranium miners.

Conclusion: Our data suggest that along with screening for pulmonary diseases, uranium industry workers should be screened for cardiovascular diseases.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Angina Pectoris / chemically induced
  • Angina Pectoris / etiology*
  • Cardiovascular Diseases / epidemiology
  • Cardiovascular Diseases / etiology
  • Cross-Sectional Studies
  • Female
  • Humans
  • Male
  • Middle Aged
  • Mining*
  • New Mexico / epidemiology
  • Occupational Diseases / epidemiology*
  • Occupational Diseases / etiology
  • Surveys and Questionnaires
  • Uranium / adverse effects*

Substances

  • Uranium