Evolution of epidermoid cyst into dermoid cyst: Embryological explanation and radiological-pathological correlation

Neuroradiol J. 2019 Apr;32(2):92-97. doi: 10.1177/1971400918821086. Epub 2019 Jan 3.

Abstract

Intracranial dermoid and epidermoid cysts are usually considered to be two different entities in the radiological and surgical literature. Epidermoid cysts are classically off midline in location, isointense to cerebrospinal fluid on T1 and T2-weighted images and have restricted diffusion, whereas dermoid cysts are classically midline in location, have T1-hyperintense regions due to the presence of fat and show facilitated diffusion. We report a case of radiological epidermoid cyst in baseline imaging, which evolved into a radiological dermoid cyst over time, and explain this unique occurrence with a review of the embryology and histopathogenesis of these cysts.

Keywords: Dermoid cyst; dermoid cyst rupture; diffusion restriction; diffusion-weighted imaging (DWI); epidermoid cyst.

Publication types

  • Case Reports

MeSH terms

  • Brain Neoplasms / diagnostic imaging*
  • Brain Neoplasms / embryology*
  • Brain Neoplasms / pathology
  • Brain Neoplasms / surgery
  • Dermoid Cyst / diagnostic imaging*
  • Dermoid Cyst / embryology*
  • Dermoid Cyst / pathology
  • Dermoid Cyst / surgery
  • Epidermal Cyst / diagnostic imaging*
  • Epidermal Cyst / embryology*
  • Epidermal Cyst / pathology
  • Epidermal Cyst / surgery
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Rupture, Spontaneous
  • Tomography, X-Ray Computed
  • Young Adult