1 Paediatric Intensive Care Unit, Lady Cilento Childrens Hospital, Brisbane, QLD, Australia, and Paediatric Critical Care Research Group, Mater Research Institute, University of Queensland, Brisbane, QLD, Australia Respiratory Critical Care and Anaesthesia Unit, UCL Great Ormond Street Institute of Child Health, London, United Kingdom, and Paediatric and Neonatal Intensive Care Units, Great Ormond Street Hospital for Children NHS Trust, London, United Kingdom.