FISHing for β Cells

Laura I Hudish; David S Lorberbaum; Lori Sussel

doi:10.1016/j.devcel.2018.12.007

FISHing for β Cells

Dev Cell. 2019 Jan 7;48(1):7-8. doi: 10.1016/j.devcel.2018.12.007.

Authors

Laura I Hudish¹, David S Lorberbaum¹, Lori Sussel²

Affiliations

¹ Barbara Davis Center for Diabetes, University of Colorado Anschutz Medical Center, Aurora, CO 80045, USA.
² Barbara Davis Center for Diabetes, University of Colorado Anschutz Medical Center, Aurora, CO 80045, USA. Electronic address: [email protected].

Abstract

β cell heterogeneity has emerged as an important contributor to islet function, with potential implications for diabetes. Using an optimized smFISH technique in intact islets, Farack et al. (2018) identify in the islet core an endocrine cell population of "extreme" β cells with distinct molecular properties.

FISHing for β Cells

Authors

Affiliations

Abstract

Publication types

MeSH terms

Grants and funding