Enzyme-assisted self-assembly within a hydrogel induced by peptide diffusion

Chem Commun (Camb). 2019 Jan 25;55(8):1156-1159. doi: 10.1039/c8cc09437c. Epub 2019 Jan 11.

Abstract

The diffusion of adequate peptide through an enzyme-embedded host hydrogel leads to the in situ start-up and growth of an interpenetrated fibrous network. Based on the enzyme-assisted self-assembly concept, both chemistry and mechanical features of the hybrid hydrogel can be tuned.

MeSH terms

  • Alkaline Phosphatase / metabolism*
  • Diffusion*
  • Hydrogels / chemistry
  • Hydrogels / metabolism*
  • Molecular Structure
  • Particle Size
  • Peptides / chemistry
  • Peptides / metabolism*
  • Polyethylene Glycols / chemistry
  • Polyethylene Glycols / metabolism
  • Surface Properties

Substances

  • Hydrogels
  • Peptides
  • Polyethylene Glycols
  • Alkaline Phosphatase