Efficacy of Baricitinib in the Treatment of Chilblains Associated With Aicardi-Goutières Syndrome, a Type I Interferonopathy

MeSH terms

• Antigens / genetics
• Antigens / immunology
• Antigens, Surface / genetics
• Antigens, Surface / immunology
• Autoimmune Diseases of the Nervous System / complications
• Autoimmune Diseases of the Nervous System / genetics
• Autoimmune Diseases of the Nervous System / immunology*
• Azetidines / therapeutic use*
• Chilblains / drug therapy*
• Chilblains / etiology
• Cytoskeletal Proteins / genetics
• Cytoskeletal Proteins / immunology
• Female
• GPI-Linked Proteins / genetics
• GPI-Linked Proteins / immunology
• Humans
• Interferon Type I / immunology*
• Intracellular Signaling Peptides and Proteins / genetics
• Intracellular Signaling Peptides and Proteins / immunology
• Janus Kinase Inhibitors / therapeutic use*
• Monocytes / immunology
• Mutation
• Myxovirus Resistance Proteins / genetics
• Myxovirus Resistance Proteins / immunology
• Nervous System Malformations / complications
• Nervous System Malformations / genetics
• Nervous System Malformations / immunology*
• Purines
• Pyrazoles
• SAM Domain and HD Domain-Containing Protein 1 / genetics
• STAT1 Transcription Factor / metabolism
• Sulfonamides / therapeutic use*
• T-Lymphocytes / immunology
• T-Lymphocytes / metabolism
• Tumor Suppressor Proteins / genetics
• Tumor Suppressor Proteins / immunology
• Young Adult