Azacitidine is effective for targeting leukemia-initiating cells in juvenile myelomonocytic leukemia

Leukemia. 2019 Jul;33(7):1805-1810. doi: 10.1038/s41375-018-0343-2. Epub 2019 Jan 24.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Antimetabolites, Antineoplastic / pharmacology*
  • Azacitidine / pharmacology*
  • Carcinogenesis / drug effects*
  • Carcinogenesis / metabolism
  • Carcinogenesis / pathology
  • Humans
  • Leukemia, Myelomonocytic, Juvenile / drug therapy*
  • Leukemia, Myelomonocytic, Juvenile / metabolism
  • Leukemia, Myelomonocytic, Juvenile / pathology
  • Mesenchymal Stem Cells / drug effects*
  • Mesenchymal Stem Cells / metabolism
  • Mesenchymal Stem Cells / pathology
  • Mice
  • Mice, Inbred BALB C
  • Neoplastic Stem Cells / drug effects*
  • Neoplastic Stem Cells / metabolism
  • Neoplastic Stem Cells / pathology
  • Tumor Cells, Cultured
  • Xenograft Model Antitumor Assays

Substances

  • Antimetabolites, Antineoplastic
  • Azacitidine