Insights into chest computed tomography findings in Behcet's disease

Tuberk Toraks. 2018 Dec;66(4):325-333. doi: 10.5578/tt.27936.

Abstract

Introduction: To evaluate the spectrum and frequency of abnormal chest multidedector computed tomography (MDCT) findings in Behcet's disease(BD).

Materials and methods: Chest MDCT scans of 44 patients referred to radiology department for chest symptoms those had prior or newly established diagnosis of BD between 2009-2016 were retrospectively reviewed. Abnormal findings within pulmonary artery (PA), lungs, other large vessels, heart, mediastinum, pleura and pericardium were noted.

Result: Sixteen patients had one ore more computed tomography (CT) findings related to BD. PA involvement was most common (27.2%) presentation revealing thrombosis in 8 and aneurysms in 4 of 12 patients. Mean PA diameter was 29 ± 3.7 mm. Patients with PA involvement had significantly higher PA diameters than those without (p< 0.001). Hypertrophied bronchial artery seen as serpiginous vessels around hilum was a common finding (66.6%). Lung parenchyma findings was rarely isolated and usually associated with PA involvement with subpleural alveolar opacities, focal atelectasis and ill-defined nodular opacities. Cardiac filling defects were accompanying lesions in most of patients with PA aneurysms (75%).

Conclusions: BD is associated with a wide spectrum of simultaneous involvement of discrete anatomical sites. PA enlargement and hypertrophied bronchial artery is a clue for patients with PA involvement. Heart chambers should be checked for filling defects particularly in patients with PA aneurysms.

MeSH terms

  • Adult
  • Behcet Syndrome / diagnosis*
  • Bronchial Arteries / diagnostic imaging*
  • Female
  • Humans
  • Lung / diagnostic imaging*
  • Male
  • Pericardium / diagnostic imaging*
  • Pulmonary Artery / diagnostic imaging*
  • Radiography, Thoracic / methods*
  • Reproducibility of Results
  • Retrospective Studies
  • Tomography, X-Ray Computed / methods*