Hypereosinophilic syndrome presenting with bilateral ear fullness

Eur Ann Otorhinolaryngol Head Neck Dis. 2019 Jun;136(3):199-201. doi: 10.1016/j.anorl.2018.03.009. Epub 2019 Jan 23.

Abstract

Introduction: Hypereosinophilic syndrome is a rare disease with hypereosinophilia resulting in end-organ dysfunction. Patients present with organ-associated symptoms, and the targets frequently affected are heart, lung, skin, or the nervous system, and the middle ear involvement is rare.

Case report: A 30-year-old female with left ear fullness and hearing loss, which persisted for 6months, was finally diagnosed with hypereosinophilic syndrome (HES). After high dose systemic steroids treatment, all symptoms improved.

Conclusion: Eosinophilic otitis media and HES involving the middle ear share many clinical manifestations. Prompt and accurate differential diagnosis is required for these diseases to ameliorate symptoms and promote recovery.

Keywords: Eosinophilia; Hypereosinophilic syndrome; Otitis media.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Female
  • Humans
  • Hypereosinophilic Syndrome / complications*
  • Hypereosinophilic Syndrome / diagnosis
  • Hypereosinophilic Syndrome / drug therapy
  • Otitis Media with Effusion / etiology*
  • Rare Diseases / complications*
  • Rare Diseases / diagnosis
  • Rare Diseases / drug therapy
  • Steroids / administration & dosage

Substances

  • Steroids