The Effect of Supraclavicular Radiotherapy on Acoustic Voice Quality Index (AVQI), Spectral Amplitude and Perturbation Values

J Voice. 2020 Jul;34(4):649.e7-649.e13. doi: 10.1016/j.jvoice.2019.01.003. Epub 2019 Jan 25.

Abstract

Objective: The Acoustic Voice Quality Index (AVQI), spectral amplitude, and voice perturbation parameters are objective assessment methods that are used in clinical settings and for research purposes. The aim of this study was to demonstrate the effect of supraclavicular RT on the physiology and function of the vocal fold.

Methods: A total of 29 female patients were included in the study. The voices of the patients, who were diagnosed with breast cancer and underwent supraclavicular RT, were recorded before and after the treatment (1 and 6 months). AVQI, spectral amplitude (H1-H2, H1-A1, H1-A2, H1-A3) and acoustic analyses of the voice perturbation parameters were performed.

Results: AVQI was significantly higher in the first month (P < 0.05). Of the voice perturbation parameters, shimmer was found to be significantly high in the first month (P < 0.05). However, not all spectral amplitude values showed a significant change (P > 0.05).

Conclusion: In this study, AVQI and shimmer values were found to be higher following the application of supraclavicular RT. These results showed that nonlaryngeal RT might cause changes in the acoustic values of the voice in the early stage.

Keywords: Acoustic Voice Quality Index; Acoustic measurement; Radiotherapy; Spectral amplitude.

MeSH terms

  • Acoustics*
  • Adult
  • Breast Neoplasms / radiotherapy*
  • Female
  • Humans
  • Middle Aged
  • Predictive Value of Tests
  • Prospective Studies
  • Radiation Injuries / diagnosis*
  • Radiation Injuries / etiology
  • Radiation Injuries / physiopathology
  • Radiotherapy / adverse effects
  • Risk Factors
  • Sound Spectrography
  • Speech Production Measurement*
  • Time Factors
  • Treatment Outcome
  • Voice Disorders / diagnosis*
  • Voice Disorders / etiology
  • Voice Disorders / physiopathology
  • Voice Quality / radiation effects*