Pipeline Embolization of an Infectious Basilar Artery Aneurysm in a 2-Year-Old Child: Case Report, Discussion of the Literature and Perioperative Considerations

Oper Neurosurg (Hagerstown). 2019 Nov 1;17(5):E224-E228. doi: 10.1093/ons/opz002.

Abstract

Background and importance: Flow diversion of intracranial aneurysms has been rarely described in the pediatric population. Here we discuss the technical and perioperative complexities inherent in the flow diversion of an infectious basilar apex aneurysm in a 2-yr-old child with significant medical comorbidities.

Clinical presentation: Following judicious oral administration of dual anti-platelet agents and intra-arterial administration of calcium channel blockers to treat vasospasm, standard endovascular procedures were used to place a flow diverting stent across the neck of a rapidly enlarging infectious aneurysm of the basilar apex.Following the uncomplicated procedure, the patient demonstrated progressive thrombosis of the previously noted basilar apex aneurysm over a 3-mo period. The patient was therefore felt to be safe to proceed with, and eventually underwent, uncomplicated orthotopic heart transplant.

Conclusion: Flow diversion of complex intracranial aneurysms in pediatric patients with significant medical comorbidities is feasible and safe; however, considerations have to be made in the pre- and perioperative care of these patients given the propensity for low-weight and complicated systemic disease processes.

Keywords: Flow diversion; Infections aneurysm; Intracranial aneurysm; Mycotic aneurysm; Pediatric aneurysm; Subarachnoid hemorrhage.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Aneurysm, Infected / diagnostic imaging
  • Aneurysm, Infected / etiology
  • Aneurysm, Infected / therapy*
  • Angiography, Digital Subtraction
  • Anti-Bacterial Agents / therapeutic use*
  • Anticoagulants / therapeutic use*
  • Basilar Artery*
  • Cerebral Angiography
  • Child, Preschool
  • Computed Tomography Angiography
  • Embolization, Therapeutic / instrumentation
  • Embolization, Therapeutic / methods*
  • Endocarditis, Bacterial / complications
  • Humans
  • Hypoplastic Left Heart Syndrome / complications
  • Intracranial Aneurysm / diagnostic imaging
  • Intracranial Aneurysm / etiology
  • Intracranial Aneurysm / therapy*
  • Magnetic Resonance Angiography
  • Magnetic Resonance Imaging
  • Male
  • Subarachnoid Hemorrhage / diagnostic imaging
  • Subarachnoid Hemorrhage / etiology
  • Subarachnoid Hemorrhage / therapy*
  • Vasospasm, Intracranial / diagnostic imaging

Substances

  • Anti-Bacterial Agents
  • Anticoagulants