Severe reduction in tacrolimus concentrations with concomitant metamizole (dipyrone) therapy in transplant patients

Eur J Clin Pharmacol. 2019 Jun;75(6):869-872. doi: 10.1007/s00228-019-02635-y. Epub 2019 Jan 29.

Ali Sigaroudi^{1

2}, Alexander Jetter³, Thomas F Mueller⁴, Gerd Kullak-Ublick³, Stefan Weiler^{3

5}

¹ Department of Clinical Pharmacology and Toxicology, University Hospital Zurich-University of Zurich, Rämistrasse 100, 8091, Zurich, Switzerland. [email protected].
² Institute of Pharmacogenetics, University of Duisburg-Essen and Essen University Hospital, Essen, Germany. [email protected].
³ Department of Clinical Pharmacology and Toxicology, University Hospital Zurich-University of Zurich, Rämistrasse 100, 8091, Zurich, Switzerland.
⁴ Division of Nephrology, University Hospital Zurich-University of Zurich, Zurich, Switzerland.
⁵ Tox Info Suisse, National Poison Centre, Associated Institute of the University of Zurich, Zurich, Switzerland.

No abstract available

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