How does acute pain influence biomechanics and quadriceps function in individuals with patellofemoral pain?

Objectives: Beside pathophysiological factors, pain is believed to play a crucial role in the progression of patellofemoral pain (PFP). However, the isolated effect of pain on biomechanics and quadriceps function has not been investigated in PFP. Thus, this study aimed to investigate the effect of pain on quadriceps function and lower limb biomechanics in individuals with PFP.

Methods: Twenty-one individuals with PFP (11 males and 10 females, age: 29.76 ± 6.36 years, height: 1.74 ± 0.09 m, mass: 70.12 ± 8.56 kg) were measured at two different occasions: when not and when experiencing acute pain. Peak quadriceps torque (concentric, eccentric and isometric) and arthrogenic muscle inhibition (AMI) were assessed. Three-dimensional motion analysis and surface electromyography of the quadriceps and hamstring muscles were collected during running, a single-leg-squat and step-down task. The normality was assessed using the Shapiro-Wilk test and a MANOVA was performed at the 95% confidence interval.

Results: AMI increased significantly in acute pain. The net muscle activation of the knee extensors and flexors decreased during running in acute pain. The lower limb biomechanics and the quadriceps torque did not change in acute pain.

Discussion: It appears that even if individuals with PFP experience pain they can still deliver maximal quadriceps contractions and maintain their moving patterns without biomechanical changes. However, the overall reduced activation of the quadriceps and the increased AMI indicate the presence of quadriceps inhibition in acute pain.