Abstract
A 25-year-old man was treated with pembrolizumab for a relapsed-refractory primary mediastinal large B-cell lymphoma. On an evaluation PET-CT scan multiple 'reversed halo signs' were noticed. No infectious cause was established and we diagnosed the lesions as pembrolizumab-induced pneumonitis, an immune-related adverse event.
MeSH terms
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Adult
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Antibodies, Monoclonal, Humanized / adverse effects*
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Antineoplastic Agents, Immunological / adverse effects*
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Humans
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Lymphoma, Large B-Cell, Diffuse / drug therapy*
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Male
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Neoplasm Recurrence, Local / drug therapy*
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Pneumonia / chemically induced*
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Pneumonia / diagnostic imaging
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Positron Emission Tomography Computed Tomography
Substances
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Antibodies, Monoclonal, Humanized
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Antineoplastic Agents, Immunological
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pembrolizumab