Staying in touch: Taking a closer look at ER-Golgi contact sites

J Cell Biol. 2019 Mar 4;218(3):729-731. doi: 10.1083/jcb.201901039. Epub 2019 Feb 7.

Abstract

ER-Golgi contact sites regulate lipid homeostasis and trafficking across the trans-Golgi network. However, their molecular nature is elusive. In this issue, Venditti et al. (2019. J. Cell Biol https://doi.org/10.1083/jcb.201812020 and https://doi.org/10.1083/jcb.201812021) shine new light on the molecular determinants coupling lipid exchange and cargo exit with maintenance of ER-Golgi contacts.

Publication types

  • Research Support, Non-U.S. Gov't
  • Comment

MeSH terms

  • Golgi Apparatus*
  • Mitochondrial Membranes
  • Phosphates
  • Protein Transport
  • trans-Golgi Network*

Substances

  • Phosphates