A case report of community-acquired Pseudomonas aeruginosa pneumonia complicated with MODS in a previously healthy patient and related literature review

Tao Wang; Yijun Hou; Ruilan Wang

doi:10.1186/s12879-019-3765-1

A case report of community-acquired Pseudomonas aeruginosa pneumonia complicated with MODS in a previously healthy patient and related literature review

BMC Infect Dis. 2019 Feb 8;19(1):130. doi: 10.1186/s12879-019-3765-1.

Authors

Tao Wang¹, Yijun Hou¹, Ruilan Wang²

Affiliations

¹ Department of Critical Care Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, Republic of China.
² Department of Critical Care Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, Republic of China. [email protected].

Abstract

Background: Pseudomonas aeruginosa is an unusual pathogen in community-acquired pneumonia, especially in previously healthy adults, but often indicates poor prognosis.

Case presentation: We report a previously healthy patient who developed severe community-acquired pneumonia (CAP) caused by P. aeruginosa. He deteriorated to septic shock and multiple organ dysfunction syndrome (MODS) quickly, complicated by secondary hematogenous central nervous system (CNS) infection. After 1 month of organ support and antipseudomonal therapy, he had significant symptomatic improvement and was discharged from hospital. During treatment, the pathogen developed resistance to carbapenems quickly and the antibiotic regimen was adjusted accordingly.

Conclusions: According to our case and related literature review, we conclude that more attention should be paid to community-acquired Pseudomonas aeruginosa pneumonia, because of its rapid progression and poor prognosis.

Keywords: CAP; MODS; Pseudomonas aeruginosa.

Publication types

Case Reports
Review

MeSH terms

Adult
Anti-Bacterial Agents / therapeutic use
Central Nervous System Bacterial Infections / complications
Central Nervous System Bacterial Infections / diagnosis
Central Nervous System Bacterial Infections / drug therapy
Central Nervous System Bacterial Infections / microbiology
Community-Acquired Infections / complications
Community-Acquired Infections / diagnosis*
Community-Acquired Infections / drug therapy
Community-Acquired Infections / microbiology
Healthcare-Associated Pneumonia / complications
Healthcare-Associated Pneumonia / diagnosis*
Healthcare-Associated Pneumonia / drug therapy
Humans
Male
Multiple Organ Failure / complications
Multiple Organ Failure / diagnosis*
Multiple Organ Failure / drug therapy
Multiple Organ Failure / microbiology
Pseudomonas Infections / diagnosis*
Pseudomonas Infections / drug therapy
Pseudomonas aeruginosa / isolation & purification*
Shock, Septic / complications
Shock, Septic / diagnosis
Shock, Septic / drug therapy
Shock, Septic / microbiology

Substances

Anti-Bacterial Agents