Prescribing Practices for Patients With Borderline Personality Disorder During Psychiatric Hospitalizations

J Pers Disord. 2020 Dec;34(6):736-749. doi: 10.1521/pedi_2019_33_405. Epub 2019 Feb 11.

Abstract

This study aimed to understand prescribing practices during acute psychiatric hospitalization in a large cohort of patients (N = 569) with borderline personality disorder (BPD) at a tertiary care psychiatry unit from January 1, 2013, through January 1, 2015. The mean number of hospitalizations per patient was 1.5 (range, 1-7). The odds of being prescribed antidepressants, antipsychotics, mood stabilizers, hypnotics, or anxiolytics were higher at discharge than at admission. The rate of psychotropic prescriptions was also higher at discharge than at admission (incidence rate ratio, 1.9). This pattern was true for the combined psychotropic and nonpsychotropic ("medical") prescriptions. Further guidelines are needed regarding optimal psychosocial, medical, and psychopharmacological care of patients with BPD during acute psychiatric hospitalizations.

Keywords: acute care; evidence-based treatment; polypharmacy; psychopharmacology.

MeSH terms

  • Antipsychotic Agents* / therapeutic use
  • Borderline Personality Disorder* / drug therapy
  • Borderline Personality Disorder* / epidemiology
  • Hospitalization
  • Humans
  • Psychotropic Drugs / therapeutic use

Substances

  • Antipsychotic Agents
  • Psychotropic Drugs