Effects of perioperative oral care on prevention of postoperative pneumonia after lung resection: Multicenter retrospective study with propensity score matching analysis

Surgery. 2019 May;165(5):1003-1007. doi: 10.1016/j.surg.2018.11.020. Epub 2019 Feb 11.

Abstract

Background: Postoperative pneumonia can be a fatal complication that may occur after lung resection in cancer patients. Some reports have shown that the incidence of postoperative pneumonia is decreased after esophageal surgery by perioperative oral care; however, there exist no data to suggest that a lack of perioperative oral care can be a risk factor for postoperative pneumonia after lung resection. To investigate the association between the preventive effect of oral care and postoperative pneumonia, we conducted a multicenter, retrospective study of lung cancer patients who underwent lung resection.

Methods: Between January 2014 and December 2016, a total of 721 patients underwent lung resections at 1 of the 6 hospitals included in our study. Among 721 patients, 280 (38.8%) received perioperative oral care, and the remaining 441 (61.2%) did not receive any such care. Propensity score matching was performed to minimize selection biases associated with the comparison of retrospective data between the oral care and control groups.

Results: Of the 721 patients, 54 (7.5%) experienced postoperative pneumonia involving 13 of the 280 patients (4.6%) in the oral care group and 41 of the 441 patients (9.3%) in the control group (P = .02). On propensity score analysis, a significant difference was also found between oral care intervention and incidence of postoperative pneumonia (P = .002).

Conclusion: Our results suggest that perioperative oral care is an effective method to decrease the occurrence of postoperative pneumonia in patients who have undergone lung resection.

Publication types

  • Evaluation Study
  • Multicenter Study

MeSH terms

  • Aged
  • Female
  • Humans
  • Lung Neoplasms / surgery
  • Male
  • Middle Aged
  • Oral Hygiene*
  • Perioperative Care / methods*
  • Pneumonectomy / adverse effects*
  • Pneumonia / epidemiology*
  • Pneumonia / etiology
  • Pneumonia / prevention & control
  • Postoperative Complications / epidemiology*
  • Postoperative Complications / etiology
  • Postoperative Complications / prevention & control
  • Propensity Score
  • Retrospective Studies
  • Risk Factors
  • Treatment Outcome