Expired Tidal Volume Variation in Extremely Low Birth Weight and Very Low Birth Weight Infants on Volume-Targeted Ventilation

Samuel Wong; Honglang Wang; Robert Tepper; Gregory M Sokol; Rebecca Rose

doi:10.1016/j.jpeds.2018.12.053

Expired Tidal Volume Variation in Extremely Low Birth Weight and Very Low Birth Weight Infants on Volume-Targeted Ventilation

J Pediatr. 2019 Apr:207:248-251.e1. doi: 10.1016/j.jpeds.2018.12.053. Epub 2019 Feb 13.

Authors

Samuel Wong¹, Honglang Wang², Robert Tepper³, Gregory M Sokol⁴, Rebecca Rose⁴

Affiliations

¹ Section of Neonatology, Indiana University, Indianapolis, Indiana. Electronic address: [email protected].
² Department of Mathematical Sciences, Indiana University-Purdue University, Indianapolis, Indiana.
³ Wells Center for Pediatric Research, Indiana University, Indianapolis, Indiana.
⁴ Section of Neonatology, Indiana University, Indianapolis, Indiana.

PMID: 30770195
DOI: 10.1016/j.jpeds.2018.12.053

Abstract

In a prospective study we describe the delivery of small tidal volumes to extremely low birth weight (ELBW) and very low birth weight (VLBW) infants using a volume-targeted ventilation mode (VTV). Tidal volume delivery was consistent for both ELBW and VLBW infants independent of gestational age, birth weight, and the target volume.

Keywords: extremely low birth weight; mechanical ventilation; neonate; premature; very low birth weight; volume-targeted; volutrauma.

MeSH terms

Exhalation / physiology*
Female
Follow-Up Studies
Gestational Age
Humans
Infant, Extremely Low Birth Weight
Infant, Newborn
Infant, Premature, Diseases / physiopathology
Infant, Premature, Diseases / therapy*
Infant, Very Low Birth Weight*
Intensive Care Units, Neonatal
Intermittent Positive-Pressure Ventilation / methods*
Male
Prospective Studies
Tidal Volume / physiology*