Tyrosine Kinase Inhibitor and Immune Checkpoint Inhibitor Responses in KIT-Mutant Metastatic Melanoma

J Invest Dermatol. 2019 Mar;139(3):728-731. doi: 10.1016/j.jid.2018.10.009. Epub 2018 Oct 25.
No abstract available

Publication types

  • Letter
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antineoplastic Agents / therapeutic use*
  • Cancer Care Facilities
  • Cohort Studies
  • Dasatinib / therapeutic use
  • Disease-Free Survival
  • Female
  • Humans
  • Imatinib Mesylate / therapeutic use
  • Male
  • Melanoma / genetics*
  • Melanoma / immunology
  • Molecular Targeted Therapy / methods
  • Mutation
  • Prognosis
  • Protein Kinase Inhibitors / therapeutic use*
  • Proto-Oncogene Proteins c-kit / genetics*
  • Pyrimidines / therapeutic use
  • Retrospective Studies
  • Skin Neoplasms / genetics*
  • Skin Neoplasms / immunology
  • Survival Analysis
  • Texas
  • Treatment Outcome

Substances

  • Antineoplastic Agents
  • Protein Kinase Inhibitors
  • Pyrimidines
  • Imatinib Mesylate
  • Proto-Oncogene Proteins c-kit
  • nilotinib
  • Dasatinib