Catheter related recurrent blood stream infection caused by linezolid-resistant, methicillin resistant Staphylococcus haemolyticus; an emerging super bug

J Pak Med Assoc. 2019 Feb;69(2):261-263.

Abstract

A 61 year male, admitted in Combined Military Hospital Rawlpindi on 12th March 2017, operated for diverticulitis became colonized with Staphylococcus haemolyticus. Patient suffered repeated septic episodes caused by the same organism during his stay in hospital. The strain was identified as methicillin resistant Staphylococcus haemolyticus (MRSH) also resistant to Linezolid by analytical profile index for Staphylococcus (API Staph) and VITEK 2 Gram positive cocci panel. The isolate was cultured from blood cultures, Central Venous Catheter (CVC) tip and skin swabs. Patient was successfully treated with injectable vancomycin and skin decolonization was acheived with chlorhexidine bath after which no episode of MRSH infection occurred. Patient had an uneventful recovery and was discharged on 21st June. His follow up visit showed clinical improvement.

Keywords: Coagulase negative Staphylococcus (CNS), Methicillin resistant S.hemolyticus (MRSH), Linezolid (LNZ) resistant, intensive care unit (ICU), Sepsis..

Publication types

  • Case Reports

MeSH terms

  • Anti-Bacterial Agents / administration & dosage
  • Baths / methods
  • Catheter-Related Infections* / microbiology
  • Catheter-Related Infections* / physiopathology
  • Catheter-Related Infections* / therapy
  • Chlorhexidine / administration & dosage*
  • Cross Infection* / microbiology
  • Cross Infection* / physiopathology
  • Cross Infection* / therapy
  • Humans
  • Injections
  • Linezolid / pharmacology
  • Male
  • Methicillin Resistance*
  • Middle Aged
  • Secondary Prevention
  • Sepsis* / microbiology
  • Sepsis* / physiopathology
  • Sepsis* / therapy
  • Staphylococcal Infections* / diagnosis
  • Staphylococcal Infections* / physiopathology
  • Staphylococcal Infections* / therapy
  • Staphylococcus haemolyticus* / drug effects
  • Staphylococcus haemolyticus* / isolation & purification
  • Vancomycin / administration & dosage*

Substances

  • Anti-Bacterial Agents
  • Vancomycin
  • Linezolid
  • Chlorhexidine