Effect of patent ductus arteriosus on pulmonary vascular disease

Congenit Heart Dis. 2019 Jan;14(1):37-41. doi: 10.1111/chd.12702.

Abstract

The hemodynamic effects of a patent ductus arteriosus (PDA) are well known including systemic hypoperfusion and volume overload on the left ventricle. This article aims to provide a review of the long-standing effect of a hemodynamically significant PDA on the pulmonary vasculature and the role of cardiac catheterization in preterm infants with a PDA and pulmonary hypertension.

Keywords: congestive heart failure; neonatology; patent ductus arteriosus; pediatrics; preterm infant; pulmonary hypertension; pulmonary vascular resistance; surgical ligation of PDA; transcatheter closure of PDA.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Cardiac Catheterization
  • Ductus Arteriosus, Patent / complications
  • Ductus Arteriosus, Patent / diagnosis
  • Ductus Arteriosus, Patent / physiopathology*
  • Humans
  • Hypertension, Pulmonary / diagnosis
  • Hypertension, Pulmonary / etiology
  • Hypertension, Pulmonary / physiopathology*
  • Infant
  • Infant, Newborn
  • Infant, Premature*
  • Pulmonary Artery / physiopathology*
  • Pulmonary Circulation / physiology*
  • Vascular Resistance / physiology*