Adult patients with de novo acute myeloid leukemia show a functional deregulation of redox balance at diagnosis which is correlated with molecular subtypes and overall survival

Haematologica. 2019 Sep;104(9):e393-e397. doi: 10.3324/haematol.2018.206821. Epub 2019 Feb 28.
No abstract available

Publication types

  • Letter

MeSH terms

  • Adult
  • Aged
  • Antimycin A / pharmacology
  • Antioxidants / metabolism
  • Female
  • Humans
  • Kaplan-Meier Estimate
  • Leukemia, Myeloid, Acute / blood*
  • Leukemia, Myeloid, Acute / genetics*
  • Leukemia, Myeloid, Acute / mortality
  • Lipid Peroxidation
  • Male
  • Middle Aged
  • Mitochondria / metabolism
  • NADPH Oxidases / metabolism
  • Onium Compounds / pharmacology
  • Oxidation-Reduction*
  • Prognosis
  • Proportional Hazards Models
  • Prospective Studies
  • Reactive Oxygen Species / metabolism
  • Rotenone / pharmacology
  • Tetradecanoylphorbol Acetate / pharmacology
  • Translocation, Genetic

Substances

  • Antioxidants
  • Onium Compounds
  • Reactive Oxygen Species
  • Rotenone
  • Antimycin A
  • diphenyleneiodonium
  • NADPH Oxidases
  • Tetradecanoylphorbol Acetate