Pneumonitis in Combined Anti-programmed Death-1 Immunotherapy and Radiation Therapy for Renal Cell Carcinoma

Cureus. 2018 Dec 18;10(12):e3748. doi: 10.7759/cureus.3748.

Abstract

Anti-programed cell death-1 (Anti-PD-1) is a promising immunotherapy for advanced cancers. Autoimmune pneumonitis is a rare but potentially serious toxicity induced by anti-PD-1 immunotherapy. We report a case of therapy-induced pneumonitis in the setting of combined nivolumab, anti-PD-1 immunotherapy, and radiation therapy for metastatic renal cell carcinoma (RCC).

Keywords: immunotherapy; nivolumab; pneumonitis; radiation therapy; renal cell carcinoma.

Publication types

  • Case Reports