Abstract
Among 300 advanced cancer patients with potential urinary tract infection (UTI), 19 had symptomatic UTI. Among remaining patients (n = 281), 21% had asymptomatic bacteriuria or candiduria, and 14% received inappropriate therapy for 279 antimicrobial days. Bacteriuria or candiduria predicted antimicrobial therapy. At 10,000 to <100,000 CFU/mL, the incidence rate ratio [IRR] was 16.9 (95% confidence interval [CI], 6.0-47.2), and at ≥100,000 CFU/mL, the IRR was 27.9 (95% CI, 10.9-71.2).
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
MeSH terms
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Aged
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Aged, 80 and over
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Anti-Bacterial Agents / therapeutic use*
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Bacteriuria / complications
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Bacteriuria / drug therapy
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Candidiasis / complications
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Candidiasis / drug therapy
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Cohort Studies
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Connecticut
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Female
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Hospitals, University
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Humans
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Inappropriate Prescribing / statistics & numerical data*
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Male
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Neoplasms / complications
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Terminal Care
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Urinary Tract Infections / complications
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Urinary Tract Infections / drug therapy*
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Urinary Tract Infections / microbiology*