Uptake of the OMERACT-OARSI Hip and Knee Osteoarthritis Core Outcome Set: Review of Randomized Controlled Trials from 1997 to 2017

J Rheumatol. 2019 Aug;46(8):976-980. doi: 10.3899/jrheum.181066. Epub 2019 Mar 1.

Abstract

Objective: To assess the uptake of the OMERACT-OARSI (Outcome Measures in Rheumatology- Osteoarthritis Research Society International) core outcome set (COS) domains in hip and/or knee osteoarthritis (OA) trials.

Methods: There were 382 trials of hip and/or knee OA identified from the ClinicalTrial.gov registry from 1997 to 2017. Frequency of COS adoption was assessed by year and per 5-yearly phases.

Results: COS adoption decreased from 61% between 1997 and 2001 to 38% between 2012 and 2016. Pain (95%) and physical function (86%) were most consistently adopted. Patient's global assessment (48%) was the principal missing domain.

Conclusion: Limited adoption of the COS domains indicates that further consideration to improve uptake is required.

Keywords: ADOPTION; CORE OUTCOME SET; DOMAIN; OMERACT; TRIAL REGISTRATION.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Arthroplasty, Replacement, Hip*
  • Arthroplasty, Replacement, Knee*
  • Humans
  • Osteoarthritis, Hip / surgery*
  • Osteoarthritis, Knee / surgery*
  • Quality of Life*
  • Randomized Controlled Trials as Topic
  • Rheumatology
  • Treatment Outcome