Comparison of Two PCR Assays for Trichomonas vaginalis

Korean J Parasitol. 2019 Feb;57(1):27-31. doi: 10.3347/kjp.2019.57.1.27. Epub 2019 Feb 26.

Abstract

PCR is known to be the most sensitive method for diagnosing Trichomonas vaginalis infections. This study aimed to compare the sensitivity of a PCR assay for trichomoniasis (HY-PCR) developed in Hanyang University with the use of a Seeplex Ace Detection Kit®, using urine collected from four Korean men with prostatic disease. Overall, HY-PCR was more sensitive than the Seeplex Kit. The use of Chelex 100 is recommended for DNA isolation in order to increase the sensitivity of the PCR test.

Keywords: DNA isolation; PCR; Trichomonas vaginalis.

Publication types

  • Comparative Study
  • Evaluation Study

MeSH terms

  • Humans
  • Male
  • Molecular Diagnostic Techniques / methods*
  • Polymerase Chain Reaction / methods*
  • Prostatic Diseases / diagnosis*
  • Prostatic Diseases / parasitology
  • Sensitivity and Specificity
  • Trichomonas Infections / diagnosis*
  • Trichomonas Infections / parasitology
  • Trichomonas vaginalis / genetics
  • Trichomonas vaginalis / isolation & purification*
  • Urine / parasitology