The effect of mydriasis on moderate-to-high myopic eyes with implantable collamer lenses V4 and V4c

Eur J Ophthalmol. 2020 May;30(3):462-468. doi: 10.1177/1120672119831218. Epub 2019 Mar 8.

Abstract

Purpose: To evaluate the vault change and anterior segment movement induced by mydriasis in moderate-to-high myopic eyes with implantable collamer lenses (ICL).

Setting: Shanghai, China.

Design: A prospective consecutive observational study.

Methods: A total of 45 eyes of 24 patients with ICL V4 implantation and 128 eyes of 65 patients with ICL V4c implantation were included and analyzed. Anterior chamber depth, posterior corneal endothelium-to-ICL distance, and vault before and after mydriasis were measured by Pentacam (Oculus, Wetzlar, Germany) at 1, 3, and 6 months after surgery.

Results: Significant vault increases and anterior chamber depth increases induced by mydriasis were noted in both ICL V4 and V4c groups at 1, 3, and 6 months postoperatively. The corneal endothelium-ICL distance increased significantly in eyes with implanted ICL V4c after mydriasis at 3 and 6 months. Moreover, mydriasis-induced vault increases were greater in the ICL V4 group than in the ICL V4c group at 3 and 6 months. In eyes with implanted ICL V4c, mydriasis-induced vault increases were significantly greater at 1 month than at 3 and 6 months.

Conclusion: Mydriasis results in a general vault increase in eyes with implanted ICLs. The adjustment of the pressure equilibrium via the central hole of the ICL V4c has an important role in vault change. The mydriasis-induced vault increases tend toward stability after 3 months postoperatively. Mydriasis is relatively safe in eyes with ICL implantation.

Keywords: Myopia; implantable collamer lenses; mydriasis.

MeSH terms

  • Adolescent
  • Adult
  • Anterior Chamber / pathology
  • Endothelium, Corneal
  • Female
  • Humans
  • Intraocular Pressure / physiology
  • Iridectomy / methods
  • Iris / surgery
  • Lasers, Solid-State / therapeutic use
  • Lens Implantation, Intraocular*
  • Male
  • Microscopy, Acoustic
  • Mydriasis / physiopathology*
  • Myopia / physiopathology
  • Myopia / surgery
  • Myopia, Degenerative / physiopathology*
  • Myopia, Degenerative / surgery*
  • Phakic Intraocular Lenses*
  • Prospective Studies
  • Slit Lamp Microscopy
  • Visual Acuity / physiology
  • Young Adult