Apoprotein D in a healthy, male population and in male myocardial infarction patients and their male, first-degree relatives

Atherosclerosis. 1986 Apr;60(1):49-53. doi: 10.1016/0021-9150(86)90086-9.

Abstract

This report examines the correlation of serum apoprotein D with other lipoprotein lipids and apoproteins in a healthy, male population and compares the levels of high density lipoprotein apoprotein D of this control population with 2 samples composed of male, acute myocardial infarction patients and their healthy, male, first-degree relatives. Highly significant correlations were observed with very low density lipoprotein lipids (negative), high density lipoprotein lipids (positive) and serum triglycerides (negative). Serum and low density lipoprotein apoprotein B was not correlated with serum apoprotein D, whereas apoprotein A-I from serum and high density lipoproteins was strongly correlated with apoprotein D. A significant reduction in high density lipoprotein apoprotein D was observed in male, myocardial infarction patients. Their male, first-degree relatives also had lower apoprotein D levels, but the difference was not significant.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Apolipoprotein A-I
  • Apolipoproteins / blood*
  • Apolipoproteins A / blood
  • Apolipoproteins D
  • Cholesterol, HDL / blood
  • Humans
  • Lipoproteins, HDL / blood
  • Male
  • Middle Aged
  • Myocardial Infarction / blood*
  • Myocardial Infarction / genetics

Substances

  • Apolipoprotein A-I
  • Apolipoproteins
  • Apolipoproteins A
  • Apolipoproteins D
  • Cholesterol, HDL
  • Lipoproteins, HDL