[Comparison of preoperative planning of radioactive seed implantation for pelvic wall recurrent gynecological malignant tumors between 3D-printing non-coplanar template and 3D-printing coplanar template]

Zhonghua Yi Xue Za Zhi. 2019 Mar 19;99(11):841-843. doi: 10.3760/cma.j.issn.0376-2491.2019.11.009.
[Article in Chinese]

Abstract

Objective: To compare the difference of preoperative planning parameters between 3D-printing non-coplanar template (3D-PNCT) and 3D-printing coplanar template (3D-PCT) in the treatment of pelvic wall recurrent gynecological malignant tumor with radioactive seeds implantation, and to guide the clinical application. Methods: From January 2016 to March 2018, 33 patients with pelvic wall recurrent gynecological malignant tumor were treated with radioactive seeds implantation assisted by 3D-printing template and in Peking University Third Hospital. All patients underwent 3D-PNCT and 3D-PCT preoperative planning. The D(90) of target remained similar for the same patient. The parameters were compared with Wilcoxon test or Kruskal-Wallis test. Results: D(90) was similar between the two groups (P>0.05). The number of inserting needles through intestine and bone in 3D-PNCT group was less than that in 3D-PCT group (0 (0-13), 0 (0-25), Z=-2.941, P<0.05;0 (0-3), 0 (0-25), Z=-2.232, P<0.05). Conclusion: For patients with gynecological malignancies with pelvic recurrence, both of the two peroperative plans could achieve prescription dose, but 3D-PNCT is more safer.

目的: 比较放射性粒子植入治疗盆壁复发妇科恶性肿瘤采用3D-打印非共面模板(3D-PNCT)和3D-打印共面坐标模板(3D-PCT)术前计划参数的差异,指导临床应用。 方法: 选取2016年1月至2018年3月北京大学第三医院应用放射性粒子植入治疗的盆壁复发妇科恶性肿瘤患者33例,共37个病灶。中位年龄50岁(32~71岁)。病灶体积为40.0(4.6~332.4)cm(3)。所有患者均进行3D-PNCT和3D-PCT术前计划设计。同一患者的两种模板计划90%靶区体积的剂量(D(90))保持近似。计划参数的比较采用Wilcoxon检验或Kruskal-Wallis检验。 结果: 两组靶区D(90)相似(P>0.05)。3D-PNCT组每例患者通过肠管针数和破骨针数均少于3D-PCT组[0(0~13),0(0~25),Z=-2.941,P<0.05;0(0~3),0(0~25),Z=-2.232,P<0.05]。 结论: 对于盆壁复发妇科恶性肿瘤患者,两种模板术前计划均可达到处方剂量,3D-PNCT引起的损伤小,应用更安全。.

Keywords: Genital neoplasms, female; Iodine radioisotopes; Neoplasm recurrence, local; Radiotherapy dosage.

Publication types

  • Comparative Study

MeSH terms

  • Female
  • Genital Neoplasms, Female
  • Humans
  • Iodine Radioisotopes
  • Neoplasm Recurrence, Local
  • Pelvic Neoplasms
  • Printing, Three-Dimensional*
  • Radiotherapy Dosage
  • Radiotherapy Planning, Computer-Assisted

Substances

  • Iodine Radioisotopes