A biological or a synthetic mesh in immediate breast reconstruction? A cohort-study of long-term Health related Quality of Life (HrQoL)

Eur J Surg Oncol. 2019 Oct;45(10):1812-1816. doi: 10.1016/j.ejso.2019.03.013. Epub 2019 Mar 15.

Abstract

Objectives: Meshes/matrices are commonly used in immediate breast reconstruction. There are few studies comparing biological and synthetic meshes and it is unknown what type of mesh gives the best long-term results. The aim of this study was to compare long-term health-related quality of life (HrQoL) and patient satisfaction in implant-based immediate breast reconstruction with a biological mesh (Surgisis®) with that of patients reconstructed with a synthetic mesh (TIGR ® Matrix Surgical Mesh).

Material and methods: Both cohorts were prospectively included and consecutively operated. Clinical data was collected. HrQoL was evaluated with EuroQoL-5 dimension - 3 levels questionnaire (EQ-5D-3L) and the Hospital Anxiety and Depression Scale (HADS) and the Breast-Q.

Results and conclusion: Seventy-one patients were operated on in the biological group and 49 in the synthetic group. The response rates were 75 and 84 per cent, respectively. Mean follow-up time was 74 months and 23 months, respectively. There were no statistical differences in satisfaction and quality of life between the two groups. Complications and radiation seem to lead to a lower satisfaction. Our findings could indicate that biological and synthetic meshes give an equal long-term result as regards patients' perceived quality of life.

Keywords: Acellular dermal matrix; Immediate breast reconstruction; Implant; Patient's satisfaction; Quality of life; Synthetic mesh; Tissue expander.

MeSH terms

  • Acellular Dermis*
  • Adult
  • Aged
  • Breast Neoplasms / surgery*
  • Collagen*
  • Female
  • Follow-Up Studies
  • Humans
  • Mammaplasty / methods*
  • Mastectomy
  • Middle Aged
  • Patient Satisfaction*
  • Prospective Studies
  • Quality of Life*
  • Surgical Mesh*
  • Tissue Expansion Devices
  • Treatment Outcome

Substances

  • surgisis
  • Collagen