Multidisciplinary therapy is considered as an acceptable option for gastric cancer patients with liver metastases currently, while the effectiveness of surgery is still controversial. Although there was no improved survival for cytoreductive surgery, some evidences showed that some selected patients with the combination surgery of gastric cancer and liver metastases could benefit from curative resection. Compared to cytoreductive surgery for gastric cancer patients with liver metastasis, curative resection did not increase the incidence of complications or mortality. Therefore, surgery-based multidisciplinary therapy would be appropriate for some seleted gastric cancer patients with liver metastasis. In highly selected patients with neoadjuvant chemotherapy, curative resection with both primary and metastatic tumor could improve long-term survival benefits. Furthermore, the long-term survival and quality of life should be considered of equal importance in future studies.
目前，胃癌肝转移患者以全身治疗为主，外科手术治疗的价值仍有争议。虽然单纯减瘤手术无法使转移性胃癌患者的生存获益，但已有证据显示，对于经选择的部分胃癌肝转移患者，联合肝转移灶切除的根治性手术能改善患者的预后。此外，与非根治性减瘤手术比较，根治性手术并未增加术后并发症的发生率和死亡率。因此，对于经选择的部分胃癌肝转移患者的治疗，应该是包括外科手术在内的综合治疗模式。挑选合适患者化疗后行联合转移灶切除的根治性手术，将会延长患者的生存时间。未来研究的开展应同时重视评价胃癌肝转移患者的生存时间和生活质量。.
Keywords: Curative resection; Cytoreductive surgery; Gastric neoplasms; Multidisciplinary therapy; Neoplasms metastasis, Liver; Prognosis.