Characterization of the novel HLA-DRB1*14:207 allele by sequencing-based typing

HLA. 2019 Jul;94(1):85-86. doi: 10.1111/tan.13539. Epub 2019 Apr 14.

Authors

Vincent Elsermans¹, Jonathan Visentin^{2

3}, Isabelle Top¹, Pauline Varlet^{1

4}, Myriam Labalette^{1

4}

Affiliations

¹ CHRU de Lille, Institut d'Immunologie-HLA, Bd du Professeur Jules Leclercq, Lille, France.
² CHU de Bordeaux, Laboratoire d'Immunologie et Immunogénétique, Hôpital Pellegrin, Place Amélie Raba Léon, Bordeaux, France.
³ UMR CNRS 5164 Immunoconcept, Université de Bordeaux, Bordeaux, France.
⁴ INSERM U995 LIRIC, Université de Lille, Lille, France.

PMID: 30932368
DOI: 10.1111/tan.13539

Abstract

HLA-DRB1*14:207 differs from HLA-DRB1*14:54:01:01 by one nucleotide substitution at codon 140 in exon 3.

Keywords: HLA-DRB1*14:207; human leukocyte antigen; novel allele; sequencing-based typing.

© 2019 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

MeSH terms

Alleles
Amino Acid Substitution
Base Sequence
Exons*
HLA-DRB1 Chains / genetics*
Hematopoietic Stem Cells / cytology*
Histocompatibility Testing / methods*
Humans
Polymorphism, Single Nucleotide*
Sequence Analysis, DNA / methods*
Sequence Homology

Substances

HLA-DRB1 Chains