Characterization of the novel HLA-DQB1*03:353 allele by sequencing-based typing

HLA. 2019 Jul;94(1):86-87. doi: 10.1111/tan.13540. Epub 2019 Apr 24.

Abstract

HLA-DQB1*03:353 differs from HLA-DQB1*03:01:01:01 by one nucleotide substitution in codon 46 in exon 2.

Keywords: HLA-DQB1*03:353; human leukocyte antigen; novel allele; sequencing-based typing.

MeSH terms

  • Alleles
  • Amino Acid Substitution
  • Base Sequence
  • HLA-DQ beta-Chains / genetics*
  • Histocompatibility Testing / methods*
  • Humans
  • Polymorphism, Single Nucleotide*
  • Sequence Analysis, DNA / methods*
  • Sequence Homology

Substances

  • HLA-DQ beta-Chains
  • HLA-DQB1 antigen