Programmed death ligand 1 is overexpressed by neutrophils in the blood of immunocompromised human immunodeficiency virus-negative patients with Pneumocystis jirovecii pneumonia

Nan-Nan Zhang; Xu Huang; Yi Zhang; Jin-Gen Xia; Min Li; Zhi-Zhi Wang; Wei Cui; Qing-Yuan Zhan

doi:10.1097/CM9.0000000000000237

Programmed death ligand 1 is overexpressed by neutrophils in the blood of immunocompromised human immunodeficiency virus-negative patients with Pneumocystis jirovecii pneumonia

Chin Med J (Engl). 2019 May 20;132(10):1237-1240. doi: 10.1097/CM9.0000000000000237.

Authors

Nan-Nan Zhang^{1

2

3

4}, Xu Huang^{1

2

3}, Yi Zhang^{1

2

3}, Jin-Gen Xia^{1

2

3}, Min Li^{1

2

3}, Zhi-Zhi Wang⁴, Wei Cui⁵, Qing-Yuan Zhan^{1

2

3

4}

Affiliations

¹ Center for Respiratory Diseases, China-Japan Friendship Hospital, Beijing 100029, China.
² Department of Pulmonary and Critical Care Medicine, China-Japan Friendship Hospital, Beijing 100029, China.
³ National Clinical Research Center for Respiratory Diseases, Beijing 100029, China.
⁴ Graduate School of Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China.
⁵ Beijing Key Laboratory of Remodeling-Related Cardiovascular Diseases, Beijing Anzhen Hospital of Capital Medical University, Beijing Institute of Heart Lung and Blood Vessel Diseases, Beijing 100029, China.

Abstract

Supplemental Digital Content is available in the text

MeSH terms

Adaptive Immunity / physiology
Aged
CD11b Antigen / metabolism
Female
HIV / pathogenicity*
Humans
Immunity, Innate / physiology
Immunocompromised Host
Male
Middle Aged
Neutrophils / metabolism*
Pneumonia, Pneumocystis / immunology
Pneumonia, Pneumocystis / metabolism*
Pneumonia, Pneumocystis / virology*
Programmed Cell Death 1 Receptor / genetics
Programmed Cell Death 1 Receptor / metabolism*

Substances

CD11b Antigen
PDCD1 protein, human
Programmed Cell Death 1 Receptor