Abstract
Seventy-three compounds were identified from the methanol extract of V. luteola, and among these, three new (1⁻3) were characterized by spectroscopic and mass spectrometric analyses. The isolated constituents were assessed for anti-inflammatory potential evaluation, and several purified principles exhibited significant superoxide anion and elastase inhibitory effects.
Keywords:
elastase release; fabaceae; sesquiterpenoid; superoxide anion generation.
MeSH terms
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Anti-Inflammatory Agents / chemistry
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Anti-Inflammatory Agents / isolation & purification
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Anti-Inflammatory Agents / pharmacology*
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Cytochalasin B / adverse effects
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Humans
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Magnetic Resonance Spectroscopy
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Mass Spectrometry
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Neutrophils / drug effects
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Neutrophils / metabolism
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Pancreatic Elastase / antagonists & inhibitors
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Phytochemicals / chemistry
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Phytochemicals / isolation & purification
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Phytochemicals / pharmacology*
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Superoxides / antagonists & inhibitors
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Vigna / chemistry*
Substances
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Anti-Inflammatory Agents
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Phytochemicals
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Superoxides
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Cytochalasin B
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Pancreatic Elastase