Bilateral Acute Depigmentation of the Iris: Findings in Anterior Segment Swept-Source Optical Coherence Tomography

Ocul Immunol Inflamm. 2019;27(8):1288-1292. doi: 10.1080/09273948.2019.1582784. Epub 2019 Apr 15.

Abstract

Objective: To describe the clinical and Anterior Segment Swept-Source Optical Coherence Tomography (AS-SS OCT) findings in Bilateral Acute Depigmentation of the Iris (BADI).Design: Retrospective descriptive study of three clinical cases.Results: Three women diagnosed with BADI shared a history of bacterial infections treated with moxifloxacin. The AS-SS OCT showed damage from the collarette to the root of the iris, without affecting the pupillary area. In the affected areas, the anterior edge had lost its homogeneous hyper-reflectivity. The stroma was thinned and showed a patchy and diffused hyper-reflectivity. The pigmentary epithelium appeared unaffected.Conclusions: AS-SS OCT findings, not previously described, locate the damage in BADI in the anterior edge and iridian stroma, areas which are rich in melanocytes and permeable to aqueous humor.

Keywords: Anterior Segment OCT; Anterior uveitis; BADI; Iris depigmentation; Swept Source.

Publication types

  • Case Reports

MeSH terms

  • Acute Disease
  • Aged
  • Anterior Eye Segment / pathology
  • Female
  • Humans
  • Hypopigmentation / pathology*
  • Iris / pathology*
  • Iris Diseases / pathology*
  • Middle Aged
  • Pigment Epithelium of Eye / pathology*
  • Tomography, Optical Coherence / methods*
  • Young Adult