Laser photocoagulation remains the standard of care for retinopathy of prematurity (ROP). Rarely, exudative retinal detachment (ERD) has been observed as a complication of laser treatment. The authors present the clinical course of an infant who developed severe, unilateral ERD after bilateral laser photocoagulation at 37 weeks postmenstrual age (PMA) for Type I ROP. The infant was managed with systemic and topical corticosteroids, and nearcomplete resolution of ERD was observed at 39 weeks. Continued follow-up until 62 weeks PMA with serial examination, fundus photography, and fluorescein angiography documented the time course of resolution and retinal sequelae of this rare complication. [Ophthalmic Surg Lasers Imaging Retina. 2019;50:242-246.].
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