Induction of innate cytokine responses by respiratory mucosal challenge with R848 in zebrafish, mice, and humans

J Allergy Clin Immunol. 2019 Jul;144(1):342-345.e7. doi: 10.1016/j.jaci.2019.04.003. Epub 2019 Apr 16.
No abstract available

Publication types

  • Clinical Trial
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Animals
  • Cytokines / immunology*
  • Female
  • Gills / drug effects
  • Gills / immunology
  • Humans
  • Imidazoles / pharmacology*
  • Immunity, Innate / drug effects
  • Immunity, Mucosal / drug effects
  • Male
  • Mice, Inbred C57BL
  • Middle Aged
  • Respiratory Mucosa / drug effects*
  • Respiratory Mucosa / immunology
  • Toll-Like Receptors / agonists*
  • Zebrafish

Substances

  • Cytokines
  • Imidazoles
  • Toll-Like Receptors
  • resiquimod