Cardiac arrest due to acute massive aortic root thrombosis after pericardial bioprosthetic aortic valve replacement

Cardiovasc Pathol. 2019 Jul-Aug:41:8-10. doi: 10.1016/j.carpath.2019.03.003. Epub 2019 Apr 1.

Abstract

Acute aortic root thrombosis extended to coronary ostia is a rare but potentially life-threatening complication of aortic valve replacement with bioprosthetic substitutes. We aimed to present the case of a 72-year-old woman with symptomatic rheumatic valve disease and associated atrial fibrillation who underwent conventional mitroaortic valve replacement with two stented bioprostheses (pericardial and porcine, respectively). Eight days after surgery, she had cardiac arrest due to ventricular fibrillation, requiring immediate cardiopulmonary resuscitation. Left ventricle akinesia by echocardiography and troponin levels up to 35,000 ng/L pointed to coronary ischemia. Emergent coronary angiography showed a subocclusion of the left main trunk, with the suspicion of aortic root thrombosis. The patient was immediately reoperated, fresh thrombi were removed from the aortic root, and the aortic Magna Ease 21-mm bioprosthesis was replaced with a stentless Solo Smart 21-mm bioprosthesis. The patient died of septic complications.

Keywords: Acute bioprosthetic thrombosis; Aortic valve replacement; Bioprosthetic valve pathology; Case report.

Publication types

  • Case Reports
  • Video-Audio Media

MeSH terms

  • Aged
  • Aortic Valve / surgery*
  • Bioprosthesis*
  • Biopsy
  • Coronary Angiography
  • Device Removal
  • Fatal Outcome
  • Female
  • Heart Arrest / diagnostic imaging
  • Heart Arrest / etiology*
  • Heart Arrest / surgery
  • Heart Valve Prosthesis Implantation / adverse effects*
  • Heart Valve Prosthesis Implantation / instrumentation*
  • Heart Valve Prosthesis*
  • Humans
  • Prosthesis Design
  • Thrombosis / diagnostic imaging
  • Thrombosis / etiology*
  • Thrombosis / surgery
  • Treatment Outcome