Primary cardiac epithelioid angiosarcoma with frond-like features: a rare and ominous radiological mimicker of benign cardiac tumors

Priyatharsini Nirmalanantham; Robin M Elliott; Brian Fitzsimons; Amit Gupta; Andrew Patterson; Yakov Elgudin; Miroslav Sekulic

doi:10.1016/j.carpath.2019.04.001

Primary cardiac epithelioid angiosarcoma with frond-like features: a rare and ominous radiological mimicker of benign cardiac tumors

Cardiovasc Pathol. 2019 Jul-Aug:41:18-20. doi: 10.1016/j.carpath.2019.04.001. Epub 2019 Apr 8.

Authors

Priyatharsini Nirmalanantham¹, Robin M Elliott¹, Brian Fitzsimons², Amit Gupta³, Andrew Patterson³, Yakov Elgudin⁴, Miroslav Sekulic⁵

Affiliations

¹ Department of Pathology, University Hospitals Cleveland Medical Center, Case Western Reserve University School of Medicine, Cleveland, OH, USA.
² Department of Anesthesiology, University Hospitals Cleveland Medical Center, Cleveland, OH, USA.
³ Department of Radiology, Division of Cardiothoracic Imaging, University Hospitals Cleveland Medical Center, Case Western Reserve University School of Medicine, Cleveland, OH, USA.
⁴ Department of Surgery, Cardiac Surgery, University Hospitals Cleveland Medical Center, Case Western Reserve University School of Medicine, Cleveland, OH, USA.
⁵ Department of Pathology, University Hospitals Cleveland Medical Center, Case Western Reserve University School of Medicine, Cleveland, OH, USA. Electronic address: [email protected].

PMID: 31005792
DOI: 10.1016/j.carpath.2019.04.001

Abstract

Most primary cardiac tumors are benign neoplasms, which generally can be differentiated from malignant neoplasms via certain radiological features. We present briefly a case of a 26-year-old man undergoing resection of a right atrial mass that based on preceding radiologic findings represent a myxoma. After pathologic examination, the lesion was determined to be an epithelioid angiosarcoma with unique frond-like architecture and multiple pedicular attachments to the atrial wall.

Keywords: Angiosarcoma; Echocardiogram; Myxoma; Primary cardiac tumor.

Publication types

Case Reports

MeSH terms

Adult
Biomarkers, Tumor / analysis
Biopsy
Diagnostic Errors
Epithelioid Cells* / chemistry
Epithelioid Cells* / pathology
Heart Neoplasms / chemistry
Heart Neoplasms / diagnostic imaging*
Heart Neoplasms / pathology
Heart Neoplasms / surgery
Hemangiosarcoma / chemistry
Hemangiosarcoma / diagnostic imaging*
Hemangiosarcoma / pathology
Hemangiosarcoma / surgery
Humans
Immunohistochemistry
Magnetic Resonance Imaging*
Male
Myxoma / diagnostic imaging*
Myxoma / pathology
Predictive Value of Tests

Substances

Biomarkers, Tumor